Latar belakang: Pada anak usia prasekolah, melakukan uji fungsi respiratori dengan bronkodilator untuk mendiagnosis asma merupakan tantangan yang sangat besar. Uji osilometri telah lama dikenal sebagai alternatif bagi pasien yang sulit melakukan manuver spirometri. Namun, uji ini belum pernah dilakukan penelitian pada anak Indonesia. Tujuan: Mengetahui performa uji osilometri dalam menegakkan diagnosis asma anak dengan batuk kronik berulang (BKB). Metode: Uji diagnosis pada anak usia 3–6 tahun terduga asma di Jakarta. Subjek dengan gejala awal BKB didiagnosis secara klinis menggunakan Pedoman Nasional Asma Anak 2022 dan diukur uji osilometri forced oscillation technique (FOT) sebelum dan setelah bronkodilator. Uji bronkodilasi didefinisikan sebagai positif jika ada perubahan setidaknya −40% pada R5, +50% pada X5, atau −80% pada AX. Selanjutnya dinilai hubungan hasil uji bronkodilator terhadap diagnosis asma klinis. Hasil: Dari 58 anak (55,2% perempuan) dengan median usia 60 (36-82) bulan, gejala asma klinis paling sering berupa BKB disertai mengi dan sesak (60,6%), sementara bukan asma klinis didominasi BKB saja (72%). Kriteria variabilitas, pencetus, dan reversibilitas lebih dominan pada asma klinis. Uji bronkodilasi positif didapatkan pada 57,6% asma klinis dan 64% bukan asma klinis. Pada asma klinis, terjadi penurunan R5 38% dan kenaikan X5 37%, sedangkan pada bukan asma klinis penurunan R5 25% dan kenaikan X5 44%. Pasca bronkodilator, sensitivitas tertinggi didapatkan pada X5 (45,45%) dan spesifisitas tertinggi pada R5 (80%). Small airway dysfunction teridentifikasi melalui penurunan R5-20 (-60%). Simpulan: Uji bronkodilasi FOT dapat mendeteksi obstruksi saluran respiratori melalui parameter R5 dan X5 yang mendukung diagnosis asma klinis pada BKB dengan spesifisitas R5 (80%) dan sensitivitas X5 (45,45%).Background: Diagnosing asthma in preschool children using bronchodilator respiratory function tests is a significant challenge. Oscillometry has long been recognized as an alternative for patients who struggle with spirometry maneuvers. However, no studies have evaluated this test in Indonesian children.

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Background: Diagnosing asthma in preschool children using bronchodilator respiratory function tests is a significant challenge. Oscillometry has long been recognized as an alternative for patients who struggle with spirometry maneuvers. However, no studies have evaluated this test in Indonesian children.

Objective: To evaluate the performance of oscillometry in diagnosing asthma in children with recurrent chronic cough (RCC).

Methods: A diagnostic study involving children aged 3–6 years suspected of asthma in Jakarta. Subjects with initial RCC symptoms were clinically diagnosed using the 2022 National Pediatric Asthma Guidelines and underwent oscillometry using the forced oscillation technique (FOT) before and after bronchodilator administration. A positive bronchodilator test was defined as a change of at least −40% in R5, +50% in X5, or −80% in AX. The relationship between bronchodilator test results and clinical asthma diagnosis was then evaluated.

Results: Among 58 children (55.2% female; median age 60 [36–82] months), clinical asthma symptoms were most commonly RCC with wheezing and shortness of breath (60.6%), while non-clinical asthma cases were predominantly RCC alone (72%). Variability, triggers, and reversibility criteria were more dominant in clinical asthma. A positive bronchodilator test was observed in 57.6% of clinical asthma cases and 64% of non-clinical asthma cases. In clinical asthma, R5 decreased by 38%, and X5 increased by 37%, whereas, in non-clinical asthma, R5 decreased by 25%, and X5 increased by 44%. Post-bronchodilator, the highest sensitivity was observed in X5 (45.45%) and the highest specificity in R5 (80%). Small airway dysfunction was identified through a reduction in R5-20 (−60%).

Conclusion: FOT bronchodilator testing effectively detects respiratory airway obstruction through R5 and X5 parameters, supporting the clinical asthma diagnosis in RCC with an R5 specificity of 80% and X5 sensitivity of 45.45%.