Situasi pandemi COVID-19 yang terjadi saat ini dapat mengakibatkan konsekuensi pada berbagai aspek kehidupan, termasuk kesehatan fisik dan mental, ekonomi, dan aspek lainnya pada setiap lapisan masyarakat. Kondisi tersebut dapat mempengaruhi kualitas hidup individu. Penelitian ini bertujuan untuk mengetahui faktor-faktor yang mempengaruhi kualitas hidup mahasiswa Fakultas Kesehatan Masyarakat Universitas Indonesia di masa pandemi COVID-19. Penelitian ini menggunakan desain penelitian cross sectional. Responden pada penelitian ini berjumlah 307 orang dengan metode pengambilan sampel purposive sampling. Kualitas hidup diukur menggunakan kuesioner WHOQOL-BREF. Hasil penelitian menunjukkan bahwa terdapat hubungan signifikan antara penghasilan (p=0,001), riwayat penyakit selain COVID-19 (p=0,006), aktivitas fisik (p=0,000), stress (p=0,000), dan dukungan sosial (p=0,000) dengan kualitas hidup mahasiswa S1 Reguler Fakultas Kesehatan Masyarakat Universitas Indonesia selama pandemi COVID-19. Sementara usia, jenis kelamin, dan status tempat tinggal tidak terdapat hubungan yang signifikan dengan kualitas hidup mahasiswa FKM UI. Pemerintah dan pihak universitas perlu mengoptimalkan kebijakan dan program untuk kesehatan masyarakatnya, baik fisik dan psikologis agar dapat meningkatkan kualitas hidup masyarakat. Serta diperlukan edukasi pada mahasiswa mengenai kualitas hidup, dan menyediakan layanan dan fasilitas yang mendukung memperbaiki kualitas hidup mahasiswa.

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The current situation of the COVID-19 pandemic can have consequences on various aspects of life, including physical and mental health, economy, and other aspects at every level of society. These conditions can affect the quality of life of individuals. This study aims to determine the factors that affect the quality of life of students of the Faculty of Public Health, University of Indonesia during the COVID-19 pandemic. This study used a cross sectional research design. Respondents in this study was 307 people with purposive sampling method. Quality of life was measured using the WHOQOL-BREF questionnaire. The results showed that there was a significant relationship between income (p=0.001), history of illness other than COVID-19 (p=0.006), physical activity (p=0.000), stress (p=0.000), and social support (p=0.000) with the quality of life of Regular Undergraduate students of the Faculty of Public Health, University of Indonesia during the COVID-19 pandemic. Meanwhile, age, gender, and residence status did not have a significant relationship with the quality of life of FKM UI students. The government and universities need to optimize policies and programs for public health, both physically and psychologically to improve the quality of life of the community. It is also necessary to educate students about the quality of life, and provide services and facilities that support improving the quality of life of students.