tudi ini bertujuan mengevaluasi masalah terkait obat di Ruang IRNA Teratai lantai 4 Selatan RSUP Fatmawati dengan menggunakan klasifikasi Pharmaceutical Care Network Europe (PCNE) V9.1 dan analisis kerasionalan penggunaan antibiotik berdasarkan alur Gyssens. Melalui pengkajian prospektif pada pasien ruang rawat inap, data diperoleh dari rekam medis pasien dan lembar instruksi harian pasien pada SIMGORS. Hasil menunjukkan permasalahan terapi pada efektivitas pengobatan, keamanan pengobatan, efektivitas biaya, pemilihan obat, dan durasi pengobatan. Ketidakrasionalan penggunaan antibiotik teridentifikasi pada moksifloksasin dan meropenem karena melebihi durasi peresepan formularium nasional. Namun, penggunaan antibiotik sefiksim ditemukan rasional sebagai terapi sulih saat pasien pulang. Saran dari studi ini melibatkan peran apoteker dalam memberikan masukkan berbasis evidence-based medicine dan edukasi formularium nasional kepada dokter. Hal ini bertujuan untuk mencegah resistensi antibiotik dan kerugian ekonomi rumah sakit.

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This study aimed to evaluate drug-related issues in the IRNA Teratai Ward, 4th Floor South of Fatmawati Hospital using the Pharmaceutical Care Network Europe (PCNE) V9.1 classification and analyze the rationality of antibiotic use based on the Gyssens flowchart. Through a prospective assessment of in-patients, data were obtained from patient medical records and daily instruction sheets on SIMGORS. The results revealed therapy problems related to treatment effectiveness, drug safety, cost-effectiveness, drug selection, and treatment duration. Irrational use of antibiotics was identified in moxifloxacin and meropenem due to exceeding the national formulary prescription duration. However, the use of cefixime was found to be rational as a replacement therapy when the patient was discharged. Recommendations from this study involve the role of pharmacists in providing evidence-based medicine feedback and educating doctors on the national formulary. This aims to prevent antibiotic resistance and financial loss to the hospital.