TB merupakan tantangan bagi pengendalian Acquired Immunodeficiency Syndrome (AIDS) karena merupakan infeksi oportunistik terbanyak pada orang dengan HIV/AIDS (ODHA). TB dapat meningkatkan progresivitas HIV dan meningkatkan risiko kematian bagi penderita HIV. Tujuan penelitian ini adalah untuk mengetahui prediktor yang berhubungan dengan kejadian TB pada ODHA di RS dr. H. Marzoeki Mahdi Bogor Tahun 2014-2016. Desain studi yang digunakan adalah cross sectional dengan menggunakan data register ART dan Rekam Medis.Sampel berjumlah 817 pasien HIV. Analisis data dilakukan dengan mengguunakan multiple cox regression.
Hasil analisis multivariat menunjukkan adanya peningkatan risiko TB pada kelompok dengan anemia (PR=1,60, 95% CI: 1,18-2,29) dibandingkan kelompok tanpa anemia, adanya status IO (PR=4,83, 95% CI: 2,30-10,61) dibandingkan kelompok tanpa IO, stadium HIV 3-4 (PR=6,38, 95% CI: 3,22-12,65) dibandingkan stadium HIV 1-2 dan kadar CD4 dengan nilai PR masing masing kategori: kadar 350-499 Vs ≥500 (PR=2,52, 95% CI: 0,33-19,34), kadar 200-349 Vs ≥500 (PR=2,71, 95% CI: 0,36-20,23), kadar <200 Vs ≥500 (PR=3,31, 95% CI: 0,45-24,37).Selain itu ditemukan adanya interaksi antara variabel stadium HIV dan status IO.
TB is a challenge for the control of Acquired Immunodeficiency Syndrome (AIDS) because it is the most common opportunistic infection in people living with with HIV (PLWH). TB increase HIV progressivity and increase the risk of death for PLWH. The purpose of this study is to determine the predictors are associated with TB among PLWH in RS dr. H. Marzoeki Mahdi Bogor, 2014-2016. Study design was cross sectional using ART register data and Medical Record. Total sample of 817 HIV patients were collected. Multiple cox regression analysis were applied in this research. The results of multivariate analysis showed an increased risk of TB in the group with anemia (PR = 1.60, 95% CI: 1.18-2.29) compared to the group without anemia, group with IO (PR = 4,83, 95% CI: 2,30-10,61) than those without IO, HIV stage 3-4 (PR = 6,38, 95% CI: 3,22-12,65) than HIV stage 1-2, and CD4 levels with PR for each category: levels of 350-499 vs ≥500 (PR = 2.52, 95% CI: 0.33-19.34), levels of 200-349 vs ≥500 (PR = 2.71, 95% CI: 0.36-20.23), levels <200 vs ≥500 (PR = 3.31, 95% CI: 0.45-24.37). In addition, there was an interaction between HIV stage and IO.