Class III malocclusion which caused by disharmonious growth of maxilla and mandible are considered as a complex and difficult case to be treated. Although there are many debates concerning the result and stability of the treatment, class III malocclusion is still a challenge to be handled. Many orthodontists agreed that treatment should be done since early ages to prevent malocclusion becoming worst which at the end will need a surgical treatment. This paper will describe the treatment of class III malocclusion on growing patients with variable of difficulties cases. Facemask as orthopedics appliance is chosen to stimulate the growth of maxilla and to modify the growth direction of mandible.