Praktik Keperawatan Klinik lanjut di ruang penyakit dalam dan poli UPT Pokdisus HIV AIDS untuk memberikan asuhan keperawatan pada klien gangguan sistem imun menggunakan model teori keperawatan Orem's Self Care Deficit menerapkan praktik keperawatan berdasarkan pembuktian Masalah keperawatan terbanyak akibat penyimpangan self care perkembangan adalah risiko infeksi dan kurang pengetahuan tentang regimen pengobatan Intervensi berdasarkan pembuktian yang diterapkan yaitu pendekatan nurse as coach menggunakan coaching technique Inovasi keperawatan yaitu penatalaksanaan aplikasi short message services sms untuk dukungan terhadap peningkatan kepatuhan terapi antireroviral Perawat menerapkan mode Self Care Deficit Orem menerapkan coaching technique untuk meningkatkan kemandirian klien dalam perawatan dirinya serta melakukan kegiatan inovatif dalam pemberian asuhan keperawatan pada klien dengan gangguan imun Kata kunci Gangguan sistem imun model Orem's self Care Deficit asuhan keperawatan

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Advance clinical practice on client with immune system disorders using model theory of Orem's Self Care Deficit is implementation of nursing practice based on evidence of nursing practice and implementing nursing innovation at the inpatient and outpatient ward setting The most frequent nursing issues occured was risk of infection and lack of knowledge about treatment of medication Nursing intervention based on evidence based practices is the the role of nurse as a coach using a coaching technique that very useful to promoting improving independency of self management Innovation of nusing in this clinical practice was using aplication of mobile phone of short message service SMS to promote the improvement of client adherence to ART Nurses apply the model of Orem's Self care Deficit apply a coaching technique to increase the independence of the client in her his care and conduct innovative activities in the provision of nursing care to clients with impaired immune systems