UI - Tesis (Open) :: Kembali

UI - Tesis (Open) :: Kembali

Ekspresi protein sitoglobin pada hati tikus yang diinduksi karbon tetraklorida dengan perlindnngan N­ Asetll Sistein =Expression of cytoglobin in rat liver treated by carbon tetrachloride and protected by N-Acetyl cystein

Asri Werdha Sari; Sri Widia Jusman, supervisor; Ani Retno Prijanti, supervisor (, 2010)
 Abstrak
[ABSTRAK

Tujuao: menganalisis ekspresi protein sitoglobin (Cygb) pada hati tikus yang mengalami stres oksidatif akibat induksi CC4 dan yang diberi perlindungan dengan antioksidao N-asetil sistein (NAC).
Hasil: stres oksidatif pada hati tikus yang diinduksi CC4 ditunjukkan oleb menurunnya aktivitas spesifik kstalase dan meningkatnya kadat senyawa dikarbonil. Titer Cygb menurun pada kelompok yang diberi CCl4. Tidak ada
perbedaan betmalma antara titer Cygb pada tikus yang dilindungl NAC sebelum
atau sesuadah CCl4.
Kesimpulan: Titer Cygb menurun pada induksi CCl4 setelah dua hari dan mendukung hipotesis bahwa Cygb berperan mencegah stres oksidatif. Penurunan titer Cygb setara dengan kerusakan oksidatif.


ABSTRACT

Aim: to analyze the expression of Cygb in rat liver under oxidative stress induced by carbon tetrochloride (CCI4) and protected by antioxidant N-acetyl cystein. Result: oxidate stress induced by CCI4 in rat liver decreases specific octivlty of catalase and increases the content of dicarbonyl. Titer of Cygb is decreased in groups induced by CCI4,. There is no significant difference in rats with NAC before and qfler CCI4.
Conclusion: Titer of Cygb is decreased qfler 2 days oxidative stress and support
the hypothesis that GYgb is play role against oxidative stress. The decrease of
Cygb titer is equal with oxidative damage.
;Aim: to analyze the expression of Cygb in rat liver under oxidative stress induced by carbon tetrochloride (CCI4) and protected by antioxidant N-acetyl cystein. Result: oxidate stress induced by CCI4 in rat liver decreases specific octivlty of catalase and increases the content of dicarbonyl. Titer of Cygb is decreased in groups induced by CCI4,. There is no significant difference in rats with NAC before and qfler CCI4.
Conclusion: Titer of Cygb is decreased qfler 2 days oxidative stress and support
the hypothesis that GYgb is play role against oxidative stress. The decrease of
Cygb titer is equal with oxidative damage.
, Aim: to analyze the expression of Cygb in rat liver under oxidative stress induced by carbon tetrochloride (CCI4) and protected by antioxidant N-acetyl cystein. Result: oxidate stress induced by CCI4 in rat liver decreases specific octivlty of catalase and increases the content of dicarbonyl. Titer of Cygb is decreased in groups induced by CCI4,. There is no significant difference in rats with NAC before and qfler CCI4.
Conclusion: Titer of Cygb is decreased qfler 2 days oxidative stress and support
the hypothesis that GYgb is play role against oxidative stress. The decrease of
Cygb titer is equal with oxidative damage.
]
 Metadata
No. Panggil : T31973
Pengarang :
Pengarang/kontributor lain :
Subjek :
Penerbitan : [Place of publication not identified]: [Publisher not identified], 2010
Program Studi :
Sumber Pengatalogan : LibUI ind rda
Tipe Konten : text
Tipe Media : unmediated
Tipe Carrier : volume
Deskripsi Fisik : xii, 51 pages : illustration ; 30 cm. + Appendix
Catatan Bibliografi : pages 49-51
Naskah Ringkas :
Lembaga Pemilik : Universitas Indonesia
Lokasi : Perpustakaan UI, Lantai 3
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No. Panggil No. Barkod Ketersediaan
T31973 15-19-065148582 TERSEDIA
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Tidak ada ulasan pada koleksi ini: 20339093